Pre-Clinical Testing

At iuvo BioScience, we share your vision to develop new modalities for the treatment or management of ocular conditions. The iuvo BioScience team collectively has broad experience in nonclinical strategy building, study design, in vitro and in vivo testing, and regulatory submission preparation for ophthalmic devices and therapeutics, including combination device/drug products. Our testing capabilities include:

  • in vitro cytotoxicity tests
  • in vivo topical ocular studies (screening, acute ocular, dose range finding, repeat dose)
  • testing by intraocular and periocular routes of administration,
  • studies for contact lenses and lens care products
  • ocular pharmacokinetics

Iuvo’s vast array of assessment tools include slit lamp evaluations, direct and indirect ophthalmoscopy, anterior and posterior segment photography, tonometry for intraocular pressure (indentation, applanation and rebound), aesthesiometry, pachymetry, and impression cytology.

Along with our internal expertise, we partner with board-certified veterinary ophthalmologists as well as local ophthalmic specialists to ensure we meet the unique needs for your product development.

Clinical Testing Services

The iuvo-Oculos team has designed and executed more than 150 ophthalmic clinical trials, including:

Anterior Segment

  • Anti-infective
    • Bacterial conjunctivitis
    • Viral conjunctivitis
  • Anti-inflammatory
    • Post-operative inflammation
    • Anterior uveitis
  • Dry Eye
  • Ocular GVHD
  • Blepharoptosis
  • Glaucoma

Posterior Segment

  • Wet AMD
  • Dry AMD
  • Posterior uveitis