Ophthalmic Preclinical Testing

At iuvo, we share your vision to develop new modalities for the treatment or management of ocular conditions. The iuvo team has broad experience in many critical aspects of preclinical development of devices and therapeutics, including combination drug – device products. Our experience includes:

  • Nonclinical strategy building
  • Study design
  • In vitro and in vivo testing, including
    • In vitro cytotoxicity tests
    • In vivo topical ocular studies (screening, acute ocular, dose range finding, repeat dose)
    • Testing by intraocular and periocular routes of administration
    • Studies for contact lenses and lens care products
    • Ocular pharmacokinetics
  • Regulatory submission preparation

iuvo’s vast array of assessment tools for conducting ocular studies include:

  • Slit lamp evaluations
  • Direct and indirect ophthalmoscopy
  • Anterior and posterior segment photography
  • Tonometry for intraocular pressure (indentation, applanation, and rebound)
  • Aesthesiometry
  • Pachymetry
  • Impression cytology

Along with our internal expertise, we partner with board-certified veterinary ophthalmologists as well as local ophthalmic specialists to ensure we meet the unique needs of your product development program. Working hand in hand with our clinical research team, we can help you all the way from research to product launch.

To contact our specialists or learn more about our services, please contact us, and we’d be happy to help you with your application.