The rabbit pyrogen test is used to assess the ability for a test sample, a test sample extract or a test sample eluate to induce a febrile response. This test continues to be used as a development and release test for products that cannot effectively be assessed using the Bacterial Endotoxin Pyrogen Test.
It is also used to assess the ability of extracts of leachables for a medical device or biomaterial to induce a febrile response in accordance with the ISO 10993 standard.
