Sensitization Testing

Sensitization is the ability for a test material to induce allergenicity or sensitization, and is part of the overall ISO-10993 biocompatibility assessment.

Sensitization testing requires multiple applications of the test material or test material extract to determine if the material will induce a hypersensitivity reaction.  Over a period of approximately 4 weeks, animals undergo induction, exposure and challenge phases to assess the allergenic properties of the test material.