Sensitization Testing

Sensitization is the ability for a test material to induce allergenicity or sensitization, and is part of the overall ISO-10993 biocompatibility assessment.

Sensitization testing requires multiple applications of the test material or test material extract to determine if the material will induce a hypersensitivity reaction.  Over a period of approximately 4 weeks, animals undergo induction, exposure and challenge phases to assess the allergenic properties of the test material.


Sensitization, Buehler/Closed Patch Test, ISO Method

Guinea Pig Maximization Test (ISO), 2 Extracts

Guinea Pig Maximization Test (ISO), 1 Extract